1-Butanol Separation from Aqueous Acetone-Butanol-Ethanol (ABE) Solutions by Freeze Concentration

Nahla Osmanbegovic, Vijaya Chandgude, Sandip Bankar, Marjatta Louhi-Kultanen*

*Corresponding author for this work

Research output: Contribution to journalArticleScientificpeer-review

3 Citations (Scopus)
95 Downloads (Pure)


The suspension freeze crystallization of aqueous 1-butanol solutions, synthetic acetone-butanol-ethanol (ABE) solutions, and ABE fermentation broth was studied as a novel concentration method that requires less energy than evaporation for water removal. The equimolar aqueous ABE solutions in a total molality range of 0–5.05 mol/kg(water) were proven to be ideal solutions based on the freezing point depression obtained. An aqueous solution of 8 wt % 1-butanol and three different types of aqueous ABE solutions (3:8:1:88 ABEW, 6:16:2:76 ABEW, and 10:17:2:71 ABEW (wt %)) were concentrated for 80 min by suspension freeze crystallization in a subcooling range from 0.24 to 1.15 °C. Freeze crystallization enabled 1-butanol separation from the generated mother liquor, which split into two liquid phases after ice separation, i.e., a water-enriched phase and a 1-butanol-enriched phase. Ice yield values were higher for higher subcooling degrees and higher initial water content in the feed solutions. 1-Butanol yields separated from the mother liquors were 9.85%, 59.46%, and 22.46% for 3:8:1:88 ABEW, 6:16:2:76 ABEW, and 10:17:2:71 ABEW, respectively, whereas two-stage freeze crystallization of the fermentation broths resulted in water removal with a maximum relative percentage of 29.5%.
Original languageEnglish
Pages (from-to)4147-4153
Number of pages7
JournalCrystal Growth and Design
Issue number6
Early online date4 May 2023
Publication statusPublished - 7 Jun 2023
MoE publication typeA1 Journal article-refereed


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