The motor control relies greatly on vast sensory input from the environment (vision, audition, touch) and on the internal state of the locomotor system through proprioception. The brain mechanisms of proprioception and roles in sensorimotor integration are still largely unknown in humans, and even more so in diseased humans. We have developed a movement actuators for neuroimaging (MEG, EEG, fMRI) to study the structure and function of the proprioception related brain network, and its plasticity to motor training, and its role in diseased (CP), and recovering (stroke) brain. We develop early identification of CP in infants, and test feasibility of proprioceptive stroke-rehabilitation. We examine interactions between cognitive loading and motor performance in CP to provide more precise judgment of their cognitive abilities. We use novel neuroimaging methods (i.a. ultrafast fMRI) and 3D-motion analysis.