Janne-Juhani Raula

  • Puumiehenkuja 2, 02150 Espoo

20042019

Research output per year

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Research Output

2019

Harmonic analysis of surface instability patterns on colloidal lignin

Kamarainen, T., Ago, M., Seitsonen, J., Raula, J., Kauppinen, E., Ruokolainen, J. & Rojas, O., 31 Mar 2019, In : Abstracts of papers of the American Chemical Society. 257, 1 p.

Research output: Contribution to journalMeeting AbstractScientificpeer-review

L-LEUCINE COATED INHALABLE TEICOPLANIN POWDERS PRODUCED BY AEROSOL FLOW REACTOR METHOD

Ugur, N., Bimbo, L. M., Saris, P., Vartiainen, V., Hirvonen, J., Kauppinen, E. I. & Raula, J., 1 Jun 2019, In : JOURNAL OF AEROSOL MEDICINE AND PULMONARY DRUG DELIVERY. 32, 3, p. A18-A19 2 p.

Research output: Contribution to journalMeeting AbstractScientificpeer-review

2018

Harmonic analysis of surface instability patterns on colloidal particles

Kämäräinen, T., Ago, M., Seitsonen, J., Raula, J., Kauppinen, E. I., Ruokolainen, J. & Rojas, O. J., 1 Jan 2018, In : Soft Matter. 14, 17, p. 3387-3396 10 p.

Research output: Contribution to journalArticleScientificpeer-review

6 Citations (Scopus)

Pulmonary administration of a dry powder formulation of the antifibrotic drug tilorone reduces silica-induced lung fibrosis in mice

Vartiainen, V., Raula, J., Bimbo, L. M., Viinamäki, J., Backman, J. T., Ugur, N., Kauppinen, E., Sutinen, E., Joensuu, E., Koli, K. & Myllärniemi, M., 10 Jun 2018, In : International Journal of Pharmaceutics. 544, 1, p. 121-128 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
1 Citation (Scopus)
2017

Aerosolization, Drug Permeation and Cellular Interaction of Dry Powder Pulmonary Formulations of Corticosteroids with Hydroxypropyl-β-Cyclodextrin as a Solubilizer

Vartiainen, V., Bimbo, L. M., Hirvonen, J., Kauppinen, E. I. & Raula, J., 2017, In : Pharmaceutical Research. 34, 1, p. 25-35 11 p., 34.

Research output: Contribution to journalArticleScientificpeer-review

8 Citations (Scopus)

Harmonic analysis of wrinkled and crumpled colloidal lignin

Kämäräinen, T., Ago, M., Seitsonen, J., Raula, J., Kauppinen, E., Ruokolainen, J. & Rojas Gaona, O., 2017.

Research output: Contribution to conferencePosterScientificpeer-review

2016

Aerosolization, Drug Permeation and Cellular Interaction of Leucine Coated Combination DPI powders

Raula, J., Vartiainen, V., Kauppinen, E. I., Bimbo, L. M. & Hirvonen, J., Jun 2016, In : JOURNAL OF AEROSOL MEDICINE AND PULMONARY DRUG DELIVERY. 29, 3, p. A6-A6 1 p.

Research output: Contribution to journalMeeting AbstractScientificpeer-review

Drug permeation and cellular interaction of amino acid-coated drug combination powders for pulmonary delivery

Vartiainen, V., Bimbo, L. M., Hirvonen, J., Kauppinen, E. I. & Raula, J., 17 May 2016, In : International Journal of Pharmaceutics. 504, 1-2, p. 89-97 9 p.

Research output: Contribution to journalArticleScientificpeer-review

9 Citations (Scopus)
75 Citations (Scopus)

Oral hypoglycaemic effect of GLP-1 and DPP4 inhibitor based nanocomposites in a diabetic animal model

Shrestha, N., Araújo, F., Shahbazi, M. A., Mäkilä, E., Gomes, M. J., Airavaara, M., Kauppinen, E. I., Raula, J., Salonen, J., Hirvonen, J., Sarmento, B. & Santos, H. A., 28 Jun 2016, In : Journal of Controlled Release. 232, p. 113-119 7 p.

Research output: Contribution to journalArticleScientificpeer-review

22 Citations (Scopus)
2015

Functionalization of Alkyne-Terminated Thermally Hydrocarbonized Porous Silicon Nanoparticles With Targeting Peptides and Antifouling Polymers: Effect on the Human Plasma Protein Adsorption

Wang, C-F., Makila, E. M., Bonduelle, C., Rytkonen, J., Raula, J., Almeida, S., Narvanen, A., Salonen, J. J., Lecommandoux, S., Hirvonen, J. T. & Santos, H. A., 2015, In : ACS Applied Materials and Interfaces. 7, 3, p. 2006-2015

Research output: Contribution to journalArticleScientificpeer-review

28 Citations (Scopus)

Multistage pH-responsive mucoadhesive nanocarriers prepared by aerosol flow reactor technology: A controlled dual protein-drug delivery system

Shrestra, N., Shahbazi, M-A., Araujo, F., Mäkilä, E., Raula, J., Kauppinen, E. I., Salonen, J. J., Sarmento, B., Hirvonen, J. T. & Santos, H. A., 2015, In : Biomaterials. 68, November 2015, p. 9-20

Research output: Contribution to journalArticleScientificpeer-review

43 Citations (Scopus)

PULMONARY COMBINATION DRUG POWDERS COATED WITH SELECTED AMINO ACIDS

Raula, J., Vartiainen, V., Pyysalo, J., Brown, D. P. & Kauppinen, E. I., 1 Aug 2015, In : JOURNAL OF AEROSOL MEDICINE AND PULMONARY DRUG DELIVERY. 28, 4, p. A6-A6 1 p.

Research output: Contribution to journalMeeting AbstractScientificpeer-review

Thermoresponsive Nanoparticles of Self-Assembled Block Copolymers as Potential Carriers for Drug Delivery and Diagnostics

Rahikkala, A., Aseyev, V., Tenhu, H., Kauppinen, E. I. & Raula, J., 2015, In : Biomacromolecules. 16, 9, p. 2750-2756

Research output: Contribution to journalArticleScientificpeer-review

27 Citations (Scopus)
2014

Injected nanoparticles: The Combination of Experimental Systems to Assess Cardiovascular Adverse Effects

Vlasova, M. A., Tarasova, O. S., Riikonen, J., Raula, J., Lobach, A. S., Borzykh, A. A., Smirin, B. V., Kauppinen, E. I., Eletskii, A. V., Herzig, K-H., Salonen, J. J., Tavi, P., Lehto, V-P. & Järvinen, K., 2014, In : European Journal of Pharmaceutics and Biopharmaceutics. 87, 1, p. 64-72

Research output: Contribution to journalArticleScientificpeer-review

16 Citations (Scopus)

Polypeptide-Based Aerosol Nanoparticles: Self-Assembly and Control of Conformation by Solvent and Thermal Annealing

Rahikkala, A., Junnila, S., Vartiainen, V., Ruokolainen, J., Ikkala, O., Kauppinen, E. & Raula, J., 2014, In : Biomacromolecules. 15, 7, p. 2607-2615 9 p.

Research output: Contribution to journalArticleScientificpeer-review

8 Citations (Scopus)

Synthesis and lectin recognition of glycosylated amphiphilic nanoparticles

Valtola, L., Rahikkala, A., Raula, J., Kauppinen, E. I., Tenhu, H. & Hietala, S., 2014, In : European Polymer Journal. 59, p. 282-289

Research output: Contribution to journalArticleScientificpeer-review

8 Citations (Scopus)
2013

Cardiovascular adverse effects of injected nanocarriers: Autonomic dysregulation

Vlasova, M. A., Tarasova, O. S., Riikonen, J., Raula, J., Lobach, A. S., Borzykh, A. A., Smirin, B. V., Kauppinen, E. I., Eletskii, A. V., Herzig, K-H., Salonen, J., Tavi, P., Lehto, V-P. & Järvinen, K., 2013, In : AUTONOMIC NEUROSCIENCE: BASIC AND CLINICAL. 177, 1

Research output: Contribution to journalArticleScientificpeer-review

Coated particle assemblies for the concomitant pulmonary administration of budesonide and salbutamol sulphate

Raula, J., Rahikkala, A., Halkola, T., Pessi, J., Peltonen, L., Hirvonen, J., Järvinen, K., Laaksonen, T. & Kauppinen, E. I., 2013, In : International Journal of Pharmaceutics. 441, 1-2, p. 248-254

Research output: Contribution to journalArticleScientificpeer-review

18 Citations (Scopus)

Gas-phase synthesis of solid state DNA nanoparticles stabilized by L-leucine

Raula, J., Hanzlikova, M., Rahikkala, A., Hautala, J., Kauppinen, E. I., Urtti, A. & Yliperttula, M., 2013, In : International Journal of Pharmaceutics. 444, 1-2, p. 155-161

Research output: Contribution to journalArticleScientificpeer-review

3 Citations (Scopus)

Reinforcing randomly oriented transparent freestanding single-walled carbon nanotube films

Mustonen, K., Nasibulin, A. G., Pudas, M., Kauppinen, M., Jiang, H., Grigoras, K., Raula, J. & Kauppinen, E. I., 2013, In : Carbon. 62, p. 513-516

Research output: Contribution to journalArticleScientificpeer-review

1 Citation (Scopus)

Self-assembly of PS-b-P4VP block copolymers of varying architectures in aerosol nanospheres

Rahikkala, A., Soininen, A. J., Ruokolainen, J., Mezzenga, R., Raula, J. & Kauppinen, E. I., 2013, In : Soft Matter. 9, 5, p. 1492-1499 8 p.

Research output: Contribution to journalArticleScientificpeer-review

22 Citations (Scopus)
2012

Hierarchical Structures in Lamellar Hydrogen Bonded LC Side Chain Diblock Copolymers

Soininen, A. J., Taniounou, I., ten Brummelhuis, N., Schlaad, H., Hadjichristidis, N., Ikkala, O., Raula, J., Mezzenga, R. & Ruokolainen, J., 2012, In : Macromolecules. 45, 17, p. 7091-7097 7 p.

Research output: Contribution to journalArticleScientificpeer-review

33 Citations (Scopus)

Hierarchical Structures of Hydrogen-Bonded Liquid-Crystalline Side-Chain Diblock Copolymers in Nanoparticles

Soininen, A. J., Rahikkala, A., Korhonen, J. T., Kauppinen, E. I., Mezzenga, R., Raula, J. & Ruokolainen, J., 2012, In : Macromolecules. 45, 21, p. 8743-8751 9 p.

Research output: Contribution to journalArticleScientificpeer-review

14 Citations (Scopus)

Preparation of amino acid nanoparticles at varying saturated conditions in an aerosol flow reactor

Raula, J., Lehtimäki, M., Karppinen, M., Antopolsky, M., Jiang, H., Rahikkala, A. & Kauppinen, E. I., 2012, In : Journal of Nanoparticle Research. 14, 7, p. article 986

Research output: Contribution to journalArticleScientificpeer-review

1 Citation (Scopus)

Selective Chemical Functionalization of Carbon Nanobuds

Anoshkin, I. V., Nasibulin, A. G., Mudimela, P. R., Raula, J., Ermolov, V. & Kauppinen, E. I., 2012, In : Carbon. 50

Research output: Contribution to journalArticleScientificpeer-review

6 Citations (Scopus)

Structure and dissolution of L-leucine-coated salbutamol sulphate aerosol particles

Raula, J., Seppälä, J., Malm, J., Karppinen, M. & Kauppinen, E. I., 2012, In : AAPS PHARMSCITECH. 13, 2, p. 707-712 6 p.

Research output: Contribution to journalArticleScientificpeer-review

10 Citations (Scopus)

Thermally Sensitive Block Copolymer Particles Prepared via Aerosol Flow Reactor Method: Morphological Characterization and Behavior in Water

Nykänen, A., Rahikkala, A., Hirvonen, S-P., Aseyev, V., Tenhu, H., Mezzenga, R., Raula, J., Kauppinen, E. & Ruokolainen, J., 2012, In : Macromolecules. 45, 20, p. 8401-8411 11 p.

Research output: Contribution to journalArticleScientificpeer-review

16 Citations (Scopus)
2011

Functional hydrophobin-coating of thermally hydrocarbonized porous silicon microparticles

Bimbo, L. M., Mäkilä, E., Raula, J., Laaksonen, T., Laaksonen, P., Strommer, K., Kauppinen, E. I., Salonen, J. J., Linder, M. B., Hirvonen, J. & Santos, H. A., Dec 2011, In : Biomaterials. 32, 34, p. 9089-9099 11 p.

Research output: Contribution to journalArticleScientificpeer-review

56 Citations (Scopus)

Intact Nanoparticulate Indomethacin in Fast Dissolving Carrier Particles by Combined Wet Milling and Aerosol Flow Reactor Methods

Laaksonen, T., Liu, P., Rahikkala, A., Peltonen, L., Kauppinen, E. I., Hirvonen, J., Järvinen, K. & Raula, J., 2011, In : Pharmaceutical Research. 28, p. 2403-2411

Research output: Contribution to journalArticleScientificpeer-review

30 Citations (Scopus)

Tailoring of Water-Soluble Cellulose-g-Copolymers in Homogeneous Medium using Single-Electron Transfer Living Radical Polymerization

Hiltunen, M. S., Raula, J. & Maunu, S-L., 2011, In : Polymer International. 60, p. 1370-1379

Research output: Contribution to journalArticleScientificpeer-review

29 Citations (Scopus)
2010

Aerosol DNA nanoparticles for use in gene therapy

Hanzlíková, M., Raula, J., Hautala, J., Kauppinen, E., Urtti, A. & Yliperttula, M., 2010, p. 1-2.

Research output: Working paperProfessional

Aerosol-processed polymeric drug nanoparticles for sustained and triggered drug release

Raula, J., Eerikäinen, H., Peltonen, L., Hirvonen, J. & Kauppinen, E., 2010, p. 1-2.

Research output: Working paperProfessional

1 Citation (Scopus)

Characterizing carrier-free DPI formulations: using laser diffraction and morphological imaging to examine aerosolization performance of carrier-free inhalation powders

Raula, J., Kauppinen, E., Huck, D., Kippax, P. & Virden, A., 2010, In : Inhalation. 4, p. 8-11

Research output: Contribution to journalArticleScientificpeer-review

Investigations on particle surface characteristics vs. dispersion behaviour of l-leucine coated carrier-free inhalable powders

Raula, J., Thielmann, F., Naderi, M., Lehto, V-P. & Kauppinen, E. I., 2010, In : International Journal of Pharmaceutics. 385, 1-2, p. 79-85

Research output: Contribution to journalArticleScientificpeer-review

39 Citations (Scopus)

Selective Covalent Bonding on Carbon NanoBuds

Raula, J., Makowska, M., Sillanpää, A., Runeberg, N., Tarus, J., Heino, M., Seppälä, E. T., Jiang, H., Lahtinen, J. & Kauppinen, E. I., 2010, In : Chemistry of Materials. 22, 15, p. 4347-4349

Research output: Contribution to journalArticleScientificpeer-review

Selective covalent functionalization of carbon nanobuds

Raula, J., Makowska, M., Lahtinen, J., Sillanpää, A., Runeberg, N., Tarus, J., Heino, M., Seppälä, E. T., Jiang, H. & Kauppinen, E. I., 10 Aug 2010, In : Chemistry of Materials. 22, 15, p. 4347-4349 3 p.

Research output: Contribution to journalArticleScientificpeer-review

11 Citations (Scopus)

Temperature-controlled release from polystyrene-block-poly(N-isopropylacrylamide)-block-polystyrene block copolymer hydrogel

Ruokolainen, J., Nykänen, A., Priimägi, A., Rahikkala, A., Hirvonen, S-P., Raula, J., Tenhu, H., Kauppinen, E. I. & Mezzenga, R., 20 Nov 2010, In : Journal of Controlled Release. 148, 1, p. e53-e54 2 p.

Research output: Contribution to journalArticleScientificpeer-review

2 Citations (Scopus)
2008

Combined synthesis and in-situ coating of nanoparticles in the gas phase

Lähde, A., Raula, J. & Kauppinen, E. I., 2008, In : Journal of Nanoparticle Research. 10, p. 121-130

Research output: Contribution to journalArticleScientificpeer-review

13 Citations (Scopus)

Gas-phase synthesis of L-leucine-coated micrometer-sized salbutamol sulphate and sodium chloride particles

Raula, J., Kuivanen, A., Lähde, A. & Kauppinen, E. I., 2008, In : Powder Technology. 187, p. 289

Research output: Contribution to journalArticleScientificpeer-review

Novel inhalation drug powders with crystalline L-leucine coating

Raula, J., Lähde, A. & Kauppinen, E. I., 2008, Particles 2008, Florida, 2008.

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Production of L-leucine nanoparticles under various conditions using an aerosol flow reactor method

Lähde, A., Raula, J. & Kauppinen, E. I., 2008, In : Journal of Nanomaterials. 2008, p. 1-9 680897.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
3 Citations (Scopus)
9 Downloads (Pure)

Simultaneous synthesis and coating of salbutamol sulphate nanoparticles with L-leucine in the gas phase

Lähde, A., Raula, J. & Kauppinen, E. I., 2008, In : International Journal of Pharmaceutics. 358, 1-2, p. 256-262

Research output: Contribution to journalArticleScientificpeer-review

The effect of relative humidity on oxidation of flaxseed oil in spray dried whey protein emulsions

Partanen, R., Raula, J., Seppänen, R., Buchert, J., Kauppinen, E. I. & Forssell, P., 2008, In : Journal of Agricultural and Food Chemistry. 56, 14, p. 5717-5722

Research output: Contribution to journalArticleScientificpeer-review

83 Citations (Scopus)
2007

Aerosol flow reactor method for the synthesis of multi-component drug nano and microparticles

Raula, J., Eerikäinen, H., Lähde, A. & Kauppinen, E. I., 2007, Nanoparticulate Drug Delivery Systems: Recent Trends and Emerging Technologies. Eds.Thassu, D., Deleers, M. & Pathak, Y. (eds.). Vol. 166. p. 111-128

Research output: Chapter in Book/Report/Conference proceedingChapterScientificpeer-review

Dispersion of novel inhalation drug powders with nanocrystalline L-leucine coating

Raula, J., Brown, D. P., Lähde, A. & Kauppinen, E. I., 2007, International Congress on Particle Technology, PARTEC 2007, Germany.

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Novel inhalation drug powders with nanocrystalline L-leucine coating

Brown, D. P., Raula, J., Lähde, A. & Kauppinen, E. I., 2007, Respiratory Drug Delivery 2007, RDD Europe 2007, France. p. 279-281

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Production of novel multicomponent pharmaceutical nano and microparticles

Raula, J., Lähde, A., Eerikäinen, H. & Kauppinen, E. I., 2007, International Congress on Particle Technology, PARTEC 2007, Germany, 2007. p. 4

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Simultaneous gas phase synthesis and coating of microparticles for drug delivery applications

Raula, J., Lähde, A. & Kauppinen, E. I., 2007, p. 69-74, (The 16th Nisshin Engineering Particle Technology International Seminar.).

Research output: Working paperProfessional

Simultaneous synthesis and coating of micrometer-sized particles in the gas phase

Raula, J., Lähde, A. & Kauppinen, E. I., 2007, p. 69-74, (The 13th SCEJ Symposium on Fluidization & Particle Processing).

Research output: Working paperProfessional