Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Altered immune landscape of cervical lymph nodes reveals Epstein-Barr virus signature in multiple sclerosis
Sarkkinen, J., Yohannes, D. A., Kreivi, N., Dürnsteiner, P., Elsakova, A., Huuhtanen, J., Nowlan, K., Kurdo, G., Linden, R., Saarela, M., Tienari, P. J., Kekäläinen, E., Perdomo, M. & Laakso, S. M., 21 Feb 2025, In: Science Immunology. 10, 104, p. eadl3604Research output: Contribution to journal › Article › Scientific › peer-review
Open Access11 Citations (Scopus) -
Anti-TIM3 with hypomethylating agent revives NK and cytotoxic CD4+T cell activity in patients with AML or MDS
Forsten, S., Ford, B., Smolander, J., Bruck, O. E., Lundgren, S., Kreutzman, A., Dufva, O., Kankainen, M., Ilander, M., Lahteenmaki, H., Kasanen, T., Klievink, J., Leitner, J., Steinberger, P., Kontro, M., Lähdesmäki, H., Sabatos-Peyton, C., Rinne, M., Porkka, K. & Peltonen, K. & 2 others, , 3 Nov 2025, In: Blood. 146, p. 1704-1705 2 p.Research output: Contribution to journal › Meeting Abstract › Scientific › peer-review
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Inborn errors of immunity underlie clonal T cell expansions in large granular lymphocyte leukemia
Bravo-Perez, C., Gurnari, C., Huuhtanen, J., Kawashima, N., Guarnera, L., Mandala, A., Williams, N. D., Haddad, C., Witt, M., Unlu, S., Brady, Z., Ogbue, O., Orland, M., Ahmed, A., Kubota, Y., Pagliuca, S., Durmaz, A., Mustjoki, S., Visconte, V. & Maciejewski, J. P., 1 May 2025, In: Journal of Clinical Investigation. 135, 9, p. 1-18 18 p., e184431.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile1 Citation (Scopus)23 Downloads (Pure) -
Single-cell analysis of aplastic anemia reveals a convergence of NK and NK-like CD8+ T cells with a disease-associated TCR signature
Lundgren, S., Huuhtanen, J., Keränen, M., Feng, X., Patel, B. A., Ryland, G. L., Fox, L. C., Bravo-Perez, C., Clemente, M., Kerr, C., Walldin, G., Dufva, O., Zaimoku, Y., Tuononen, T., Myllymäki, M., Ebeling, F., Jokinen, E., Heinonen, M., Kasanen, T. & Klievink, J. & 14 others, , 26 Feb 2025, In: Science Translational Medicine. 17, 787, p. 1-17 17 p., eadl6758.Research output: Contribution to journal › Article › Scientific › peer-review
6 Citations (Scopus)1 Downloads (Pure) -
Comparison of Anti-PD1, Anti-CTLA4 and Anti-TIM3 in Treatment of AML Patients with Single-Cell Transcriptomics Displays Different Effects on Immune Subtypes
Forsten, S., Penter, L., Bruck, O. E., Smolander, J., Peltonen, K., Lahdesmaki, H., Kontro, M., Porkka, K., Abbas, H. A., Wu, C. J., Huuhtanen, J. & Mustjoki, S., 5 Nov 2024, In: Blood. 144, Supplement 1, p. 1529–1530 2 p.Research output: Contribution to journal › Meeting Abstract › Scientific › peer-review
2 Citations (Web of Science)
Press/Media
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Levinneen melanooman hoitoon uusi lääke
Huuhtanen, J. & Lähdesmäki, H.
20/02/2023
1 item of Media coverage
Press/Media: Media appearance
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Hus kehitti vaikutustavaltaan uuden lääkkeen levinneen melanooman hoitoon
17/02/2023
1 item of Media coverage
Press/Media: Media appearance
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New medication for the treatment of advanced melanoma
Lähdesmäki, H. & Huuhtanen, J.
17/02/2023 → 17/02/2023
2 items of Media coverage
Press/Media: Media appearance
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Suomessa kehitetty tekoälymalli ennustaa, kuka melanoomapotilaista hyötyy kalliista lääkkeestä ja kenen syöpä uusiutuu
02/12/2022
1 item of Media coverage
Press/Media: Media appearance
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Finnish firms seek better therapies
Huuhtanen, J. & Lähdesmäki, H.
03/11/2022 → 03/11/2022
2 items of Media coverage
Press/Media: Media appearance