Research output

Research output per year 1998 1999 2000 2001 2002 2013

• 33 Article
• 18 Working paper
• 5 Conference article in proceedings
• 4 Meeting Abstract
• 3 More
  • 2 Patent
  • 1 Paper

Research output per year

Research output per year

Search results

• 2013

  An in vitro study of composites of poly(L-lactide-co-e-caprolactone), ß-tricalcium phosphate and cipro-floxacin intended for local treatment of osteomyelitis

  Ahola, N., Männistö, N., Veiranto, M., Karp, M., Rich, J., Efimov, A., Seppälä, J. & Kellomäki, M., 2013, In: Biomatter. 3, 1, p. 1-13

  Research output: Contribution to journal › Article › Scientific › peer-review

• Hydrolytic degradation of composites of poly(L-lactide-co-epsilon-caprolactone) 70/30 and beta-tricalcium phosphate

  Ahola, N., Veiranto, M., Rich, J., Efimov, A., Hannula, M., Seppälä, J. & Kellomäki, M., 2013, In: JOURNAL OF BIOMATERIALS APPLICATIONS. 28, 4, p. 529-543 15 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
  15 Citations (Scopus)
• 2012

  Hyperelastic Property Measurements of Heat-Cured Silicone Adhesives by Cyclic Uniaxial Tensile Test

  Li, J., Tarvainen, T., Rich, J., Turunen, M. & Paulasto-Kröckel, M., 2012, In: Journal of Electronic Materials. 41, 9, p. 2613-2620

  Research output: Contribution to journal › Article › Scientific › peer-review
  2 Citations (Scopus)

• Processing and sustained in vitro release of rifampicin containing composites to enhance the treatment of osteomyelitis

  Ahola, N., Veiranto, M., Männistö, N., Karp, M., Rich, J., Efimov, A., Seppälä, J. & Kellomäki, M., 2012, In: Biomatter. 2, 4, p. 213-225

  Research output: Contribution to journal › Article › Scientific › peer-review

  9 Citations (Scopus)
• 2011

  Chemical modification of fine paper base with amphiphilic copolymer

  Vesterinen, A.-H., Anttila, M., Littunen, K., Rich, J. & Seppälä, J., 2011, In: Nordic Pulp and Paper Research Journal. 26, 4, p. 476-484 9 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  2 Citations (Scopus)

• Effect of block composition on thermal properties and melt viscosity of poly(2-(dimethylamino)ethyl methacrylate), poly(ethylenen oxide) and poly(propylene oxide) block co-polymers

  Vesterinen, A., Lipponen, S., Rich, J. & Seppälä, J., 2011, In: Express Polymer Letters. 5, 9, p. 754-765 12 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
  18 Citations (Scopus)

• Modification of fiber surface with amphiphilic polymers containing poly([2--(methacryloyloxy)ethyl] trimethyl ammonium iodide)

  Vesterinen, A.-H., Rojas, O. J., Rich, J. & Seppälä, J., 2011, 241st National Meeting and Exposition of the American-Chemical-Society (ACS). (ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY; vol. 241).

  Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific
• 2010

  Chemically Modified Polylactones for Controlled Drug Delivery Applications and for Rapid Prototyping of Bioactive Scaffolds

  Seppälä, J., Hakala, R., Korhonen, H., Malin, M. & Rich, J., 2010.

  Research output: Working paper › Professional

  • Biomaterial 100%
  • Rapid Prototyping 100%

• Modification of dextran using click-chemistry approach in aqueous media

  Pahimanolis, N., Vesterinen, A.-H., Rich, J. & Seppala, J., 2010, In: Carbohydrate Polymers. 82, 1, p. 78-82 5 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
  41 Citations (Scopus)

• Modification of Polysaccharides Using Click-Chemistry Approach in Aqueous Media

  Pahimanolis, N., Vesterinen, A.-H., Rich, J., Hippi, U. & Seppälä, J., 2010.

  Research output: Working paper › Professional

• Poly(ethylene oxide)-block-poly[2-(dimethylamino)ethyl methacrylate] as Strengthening Agent in Paper: Dynamic Mechanical Characterization

  Vesterinen, A.-H., Rich, J., Myllytie, P., Laine, J. & Seppälä, J., 2010, In: Macromolecular Materials and Engineering. 295, 3, p. 269-275 7 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
  7 Citations (Scopus)

• Synthesis and solution rheology of poly[(stearyl methacrylate)-stat-([2-(methacryloyloxy)trimethyl ammonium iodide)]

  Vesterinen, A.-H., Rich, J. & Seppälä, J., 2010, In: Journal of Colloid and Interface Science. 351, 2, p. 478-484 7 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
  12 Citations (Scopus)
• 2009

  Porous Biodegradable Scaffold: Predetermined Porosity by Dissolution of Poly(ester-anhydride) Fibers from Polyester Matrix

  Rich, J., Korhonen, H., Hakala, R., Korventausta, J., Elomaa, L. & Seppälä, J., 2009, In: Macromolecular Bioscience. 9, 7, p. 654-660 7 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
  17 Citations (Scopus)

• Rheological properties of water-soluble methacrylate block-copolymers

  Vesterinen, A.-H., Rich, J. & Seppälä, J., 2009, In: Annual Transactions of the Nordic Rheology Society. 17, p. 87-91

  Research output: Contribution to journal › Article › Scientific › peer-review
• 2008

  Bioactive glass induced in vitro apatite formation on composite GBR membranes

  Tirri, T., Rich, J., Wolke, J., Seppälä, J., Yli-Urpo, A. & Närhi, T. O., 2008, In: Journal of Materials Science: Materials in Medicine. 19, 8, p. 2919-2923 5 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
  10 Citations (Scopus)

• Controlled Porosity with poly(ester-anhydride) porogen

  Rich, J., Korhonen, H., Hakala, R. & Seppälä, J., 2008, (8th World Biomaterials Congress, Amsterdam, The Netherlands 28.05-01.06.2008).

  Research output: Working paper › Professional
• 2007

  40 vuotta Polymeeriteknologiaa TKK:lla

  Seppälä, J., Löfgren, B. & Rich, J., 2007, In: Muovi/Plast. 7, p. 25

  Research output: Contribution to journal › Article › Professional

• Biodegradable fibers used as porogen in TE scaffolds

  Rich, J., Korhonen, H., Hakala, R. & Seppälä, J., 2007, p. 23, (ScanBalt Biomaterials Days, Turku, 26.-28.9.2007).

  Research output: Working paper › Professional

• In vivo behavior of poly(epsilon-caprolactone-co-DL-lactide)/bioactive glass composites in rat subcutaneous tissue

  Ranne, T., Tirri, T., Yli-Urpo, A., Närhi, T. O., Laine, V. J. O., Rich, J., Seppälä, J. & Aho, A., 2007, In: JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS. 22, 3, p. 249-264 16 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
  14 Citations (Scopus)

• Poly(ester-anhydride) fibers used as porogen in TE scaffolds

  Rich, J., Korhonen, H., Hakala, R. & Seppälä, J., 2007, p. TESP28, (21st European Society for Biomaterials, Brighton, 9.-13.9.2007).

  Research output: Working paper › Professional
• 2004

  Injectable bioactive glass/biodegradable polymer composite for bone and cartilage reconstruction: Concept and experimental outcome with thermoplastic composites of poly(epsilon-caprolactone-co-D,L-lactide) and bioactive glass S53P4

  Aho, A. J., Tirri, T., Kukkonen, J., Strandberg, N., Rich, J., Seppälä, J. & Yli-Urpo, A., 2004, In: Journal of Materials Science: Materials in Medicine. 15, 10, p. 1165-1173 9 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• In vitro Ca-P precipitation on biodegradable thermoplastic composite of poly(epsilon-caprolactone-co-DL-lactide) and bioactive glass (S53P4)

  Jaakkola, T., Rich, J., Tirri, T., Närhi, T., Jokinen, M., Seppälä, J. & Yli-Urpo, A., 2004, In: Biomaterials. 25, 4, p. 575-581 7 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
  67 Citations (Scopus)
• 2003

  Bone response to degradable thermoplastic composite in rabbits

  Närhi, T. O., Jansen, J. A., Jaakkola, T., de Ruijter, A., Rich, J., Seppälä, J. & Yli-Urpo, A., 2003, In: Biomaterials. 24, 10, p. 1697-1704 8 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
  31 Citations (Scopus)

• In vitro evaluation of P(AGU/CL) and P(AMY/CL) copolymers, and their composites consisting of bioactive glass

  Rich, J., Kylmä, J., Gädda, T., Mikkonen, H., Peltonen, S. & Seppälä, J., 2003, p. 63, (European Society for Biomaterials Conference, Stuttgart, Germany, October 1.-4., 2003).

  Research output: Working paper › Professional

• Release of Ibuprofen from Poly(epsilon-caprolactone-co-D,L-lactide) and Simulation of the Release

  Ahola, N., Rich, J., Karjalainen, T. & Seppälä, J., 2003, In: Journal of Applied Polymer Science. 88, 5, p. 1279-1288 10 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
  15 Citations (Scopus)
• 2002

  Biologic behavior of a new degradable thermoplastic composite in rabbits.

  Närhi, T., Jansen, J. A., Jaakkola, T., de Ruijter, A., Ooms, E., Rich, J., Seppälä, J. & Yli-Urpo, A., 2002, In: Journal of Dental Research. 81, p. A311-A311 1 p.

  Research output: Contribution to journal › Meeting Abstract › Scientific › peer-review

• Dentin mineralization with a bioactive composite

  Närhi, T., Tirri, T., Rich, J. & Seppälä, J., 2002, In: Key Engineering Materials. 218-220, p. 461-464 4 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• In vitro evaluation of poly(epsilon-caprolactone-co-DL-lactide)/bioactive glass composites

  Rich, J., Jaakkola, T., Tirri, T., Närhi, T., Yli-Urpo, A. & Seppälä, J., 2002, In: Biomaterials. 23, 10, p. 2143-2150 8 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
  113 Citations (Scopus)

• In vitro proliferation of the human fibroplasts on the P(epsilon-CL-co-D,L-LA)/bioactive glass composites

  Jaakkola, T., Hormia, M., Närhi, T., Rich, J., Seppälä, J. & Yli-Urpo, A., 2002, In: Key Engineering Materials. 218-220, p. 261-264 4 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Iteration of human fibroblasts on poly(e-caprolactone-co-D,L-lactide)/bioactive glass composites with or without precorrosion

  Jaakkola, T., Hormia, M., Närhi, T., Rich, J., Seppälä, J. & Yli-Urpo, A., Mar 2002, In: Journal of Dental Research. 81, p. A392-A392 1 p.

  Research output: Contribution to journal › Meeting Abstract › Scientific › peer-review

• Lactic acid based PEU/HA and PEU/BCP composites: dynamic mechanical characterization of hydrolysis

  Rich, J., Tuominen, J., Kylmä, J., Seppälä, J., Nazhat, S. N. & Tanner, K. E., 2002, In: Journal of Biomedical Materials Research Part B: Applied Biomaterials. 63, 3, p. 346-353 8 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
  11 Citations (Scopus)

• Model Compound Release from DL-Lactide/Epsilon-Caprolactone Copolymers and Evaluation of Spesific Interactions by Molecular Modeling

  Rich, J., Karjalainen, T., Ahjopalo, L. & Seppälä, J., 2002, In: Journal of Applied Polymer Science. 86, 1, p. 1-9 9 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Osteoblast-like cell culture on differentially precorroded bioactive composites

  Meretoja, V. V., Tirri, T., Närhi, T. O., Rich, J., Seppälä, J. & Yli-Urpo, A., 2002, p. p. L20, (European Society for Biomaterials, Barcelona; 11.-14.9.2002).

  Research output: Working paper › Professional

• Release of model drugs from copolymers with high and low lactide content

  Rich, J., Kortesuo, P., Kiesvaara, J. & Seppälä, J., 2002, p. 86, (European Society for Biomaterials, Barcelona, 11.-14.9.2002).

  Research output: Working paper › Professional
• 2001

  Bioactive glass-polymer composite for experimental bone reconstruction

  Aho, A. J., Tirri, T., Seppälä, J., Rich, J., Strandberg, N., Jaakkola, T., Närhi, T. & Kukkonen, J., 2001, In: Key Engineering Materials. 192-195, p. 685-688 4 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Bioaktiivinen lasi injektoituna kopolymeerikomposiittina ja granula-muodossa kokeellisessa radiuksen segmenttidefektissä

  Kukkonen, J., Aho, A., Strandberg, N., Tirri, T., Rich, J., Seppälä, J., Yli-Urpo, A., Hautamäki, M. & Rekola, J., 2001, In: Suomen Ortopedia ja Traumatologia. 24, 4, p. 535-537

  Research output: Contribution to journal › Article › Professional

• Biodegradable material

  Seppälä, J. (Inventor), Karjalainen, T. (Inventor), Rich, J. (Inventor), Korhonen, H. (Inventor) & Ahola, N. (Inventor), 27 Aug 2001, IPC No. A61K 9/ 00 A N, Patent No. AU3746501, Priority date 14 Feb 2001, Priority No. WO2001FI00141

  Research output: Patent

• Biodegradable material

  Ahola, N. (Inventor), Karjalainen, T. (Inventor), Korhonen, H. (Inventor), Rich, J. (Inventor) & Seppälä, J. (Inventor), 2001, Patent No. WO 0160425

  Research output: Patent

• Dynamic mechanical characterization of lactic acid based PEU/HA and PEU/BCP composites in hydrolysis

  Rich, J., Tuominen, J., Kylmä, J., Seppälä, J., Nazhat, S. N. & Tanner, K. E., 2001, European Society for Biomaterials, Lontoo, 12.-14.9.2001. p. s. T215

  Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review

• Effect of the molecular weight of poly(epsilon-caprolactone-co-DL-lactide) on toremifene citrate release from copolymer/silica xerogel composites

  Rich, J., Kortesuo, P., Ahola, M., Yli-Urpo, A., Kiesvaara, J. & Seppälä, J., 2001, In: International Journal of Pharmaceutics. 212, 1, p. 121-130 10 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Inability of transforming growth factor-beta 1, combined with a bioabsorbable polymer paste, to promote healing of bone defects in the rat distal femur

  Tielinen, L., Manninen, M. J., Puolakkainen, P., Kellomäki, M., Törmälä, P., Rich, J., Seppälä, J. & Rokkanen, P., 2001, In: Archives of Orthopaedic and Trauma Surgery. 121, 4, p. 191-196 6 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• In Vitro Apatite Formation on Biodegradable GBR Membrane

  Tirri, T., Närhi, T., Wolke, J., Rich, J., Seppälä, J., Jansen, J. & Yli-Urpo, A., 2001, 2001 Annual Meeting of Society for Biomaterials, Minnesota, USA, 25.-29.4.2001. p. 1

  Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review

• In vitro biocompatibility of lactic acid based PEU/HA and PEU/BCP composites

  Rich, J., Tuominen, J., Kylmä, J., Seppälä, J., Tanner, K. E. & Di Silvio, L., 2001, p. s. P66, (European Society for Biomaterials, Lontoo, 12.-14.9.2001).

  Research output: Working paper › Professional

• Pre-treated bioactive composite in rat soft tissue

  Tirri, T., Jaakkola, T., Närhi, T., Rich, J., Seppälä, J. & Yli-Urpo, A., 2001, In: Key Engineering Materials. 192-195, p. 653-656 4 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  • Composite Material 100%
  • Tissue 100%
  • Calcium 100%
  • Enalapril Maleate 100%
  • Soft Tissue 100%

• Release of model compounds from modified lactone copolymers

  Karjalainen, T., Rich, J. & Seppälä, J., 2001, In: Journal of Applied Polymer Science. 81, 9, p. 2118-2126 9 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
• 2000

  Apatite formation on a new bioactive composite in vitro

  Tirri, T., Jaakkola, T., Rich, J., Seppälä, J., Närhi, T. & Yli-Urpo, A., May 2000, In: Journal of Dental Research. 79, 5, p. 1299-1299 1 p.

  Research output: Contribution to journal › Meeting Abstract › Scientific › peer-review

• Bioabsorbable polylactide pins with polymer paste, containing transforming growth factor-b1, in the healing of osteotomies and bone defects

  Tielinen, L., Manninen, M. J., Puolakkainen, P., Rokkanen, P., Pätiälä, H., Pihlajamäki, H., Kellomäki, M., Törmälä, P., Pohjonen, T., Rautavuori, J., Rich, J. & Seppälä, J., 2000, p. 193, (Nordic Orthopedic Federation 50th Congress, Tampere, 7.-10.6.2000).

  Research output: Working paper › Professional

• Biologic behavior of the biodegradable composite in the experimental bone defects in rabbits

  Jaakkola, T., Närhi, T. O., Jansen, J., de Ruijter, A., Ooms, E., Rich, J., Seppälä, J. & Yli-Urpo, A., 2000, XVII Turun lääketiedepäivät, Turku, 7.-9.11.2000. p. 1

  Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review

• In vitro behaviour of a thermoplastic bioactive composite

  Tirri, T., Jaakkola, T., Närhi, T., Rich, J., Seppälä, J. & Yli-Urpo, A., 2000, p. 1, (6th World Biomaterials Congress, Kamuela, USA, 15.-20.5.2000).

  Research output: Working paper › Professional

• Proliferation of osteoblast like cells on a new thermoplastic bioactive composite

  Närhi, T., de Ruijter, N., Jaakkola, T., Rich, J., Seppälä, J., Jansen, J. & Yli-Urpo, A., 2000, In: Journal of Dental Research. 79, p. 560-560 1 p., 3329.

  Research output: Contribution to journal › Meeting Abstract › Scientific