20002019

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

2019

PROCESS FOR THE PREPARATION OF ARYL SULFONYLPROPENENITRILES BY PHOTOCATALYTIC REAC­TIONS

Aaltonen, T., Kallatsa, O., Simell, J., Sneitz, N., Konn, J., Hiltunen, J. & Koskinen, A., 2019, IPC No. C07C 317/ 14 A I, Patent No. WO2019043289, 27 Aug 2018, Priority date 29 Aug 2017, Priority No. FI20170005768

Research output: Patent

Synthesis of the C1-C12 Fragment of Calyculin C

Konstantinova, O. V. & Koskinen, A. M. P., 1 Jan 2019, In : Synthesis (Germany). 51, 1, p. 285-295 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
104 Downloads (Pure)
2018

Copper Catalyzed Alcohol Oxidation and Cleavage of β-O-4 Lignin Model Systems: From Development to Mechanistic Examination

Salonen, H. E. P., Mecke, C. P. A., Karjomaa, M. I., Joensuu, P. M. & Koskinen, A. M. P., 30 Nov 2018, In : ChemistrySelect. 3, 44, p. 12446-12454 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
2 Citations (Scopus)
27 Downloads (Pure)
2015

Discovery of MINC1, a GTPase-Activating Protein Small Molecule Inhibitor, Targeting MgcRacGAP

van Adrichem, A. J., Fagerholm, A., Turunen, L., Lehto, A., Saarela, J., Koskinen, A., Repasky, G. A. & Wennerberg, K., 2015, In : COMBINATORIAL CHEMISTRY AND HIGH THROUGHPUT SCREENING. 18, 1, p. 3-17

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
3 Citations (Scopus)
130 Downloads (Pure)

Enantiospecific Gram Scale Synthesis of (S)-Eleagnine

Lood, C. S., Nieger, M. & Koskinen, A. M. P., 2015, In : Tetrahedron. 71, 30, p. 5019-5024

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
7 Citations (Scopus)
391 Downloads (Pure)
15 Citations (Scopus)

Palladium Catalyzed Direct C-H Arylation of Dicyanobenzenes

Ihanainen, N. E., Kumpulainen, E. T. T. & Koskinen, A. M. P., 2015, In : European Journal of Organic Chemistry. 2015, 15, p. 3226-3229

Research output: Contribution to journalArticleScientificpeer-review

5 Citations (Scopus)

Synthesis of chiral 2-indolyl methanamines and insight into the stereochemistry protecting effects of the 9-phenyl-9-fluorenyl protecting group

Lood, C. S., Laine, A. E., Högnäsbacka, A., Nieger, M. & Koskinen, A. M. P., 2015, In : European Journal of Organic Chemistry. 2015, 17, p. 3793-3805

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
5 Citations (Scopus)
146 Downloads (Pure)

The Tishchenko Reaction

Koskinen, A. M. P. & Kataja, A. O., 2015, Organic Reactions. 1 ed. John Wiley and Sons Inc., Vol. 86. p. 105-409 305 p. (Organic Reactions; vol. 86, no. 1).

Research output: Chapter in Book/Report/Conference proceedingChapterScientificpeer-review

14 Citations (Scopus)

Upgrading fast pyrolysis bio-oil quality by esterification and azeotropic water removal

Sundqvist, T., Oasmaa, A. & Koskinen, A., 2015, In : Energy and Fuels. 29, 4, p. 2527-2534

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
30 Citations (Scopus)
313 Downloads (Pure)

Versatile Synthesis of Symmetrical Carbazole Based Ligand Precursors via Regioselective Aromatic Bromination

Rembiak, A. & Koskinen, A. M. P., 2015, In : SYNTHESIS: STUTTGART. 47, 21, p. 3347-3353

Research output: Contribution to journalArticleScientificpeer-review

2014

Boron Enolate Chemistry toward the Syntheses of Polyketide Stereotetrads

Koskinen, A. M. P., 2014, In : CHEMICAL RECORD. 14, 1, p. 52-61

Research output: Contribution to journalArticleScientificpeer-review

7 Citations (Scopus)
Open Access
File
13 Citations (Scopus)
107 Downloads (Pure)

Development of a proof-of-concept small molecule inhibitor of MgcRacGAP identifies new potential functions of MgcRacGAP in cell division and signaling

van Adrichem, A., Fagerholm, A., Turunen, L., Lehto, A., Saarela, J., Koskinen, A., Repasky, G. & Wennerberg, K., Dec 2014, In : MOLECULAR BIOLOGY OF THE CELL. 25, 1 p.

Research output: Contribution to journalMeeting AbstractScientificpeer-review

Erratum: Synthesis of (S)- and (R)-Harmicine from Proline: An Approach Toward Tetrahydro-beta-carbolines

Lood, C. S. & Koskinen, A. M. P., Aug 2014, 1 p.

Research output: Other contributionScientificpeer-review

Pharmacological Importance of Optically Active Tetrahydro-beta-carbolines and Synthetic Approaches to Create the C1 Stereocenter

Laine, A. E., Lood, C. & Koskinen, A. M. P., 2014, In : MOLECULES. 19, 2, p. 1544-1567

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
File
61 Citations (Scopus)
101 Downloads (Pure)

Scalable synthesis of (-)-trans-3-hydroxypipecolic acid via a useful chiral building block

Karjalainen, O. K. & Koskinen, A. M. P., 2014, In : Tetrahedron. 70, 14, p. 2444-2448

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
7 Citations (Scopus)
147 Downloads (Pure)

Synthesis of ( S)-and ( R)- Harmicine from Proline: An Approach Toward Tetrahydro- beta- carbolines

Lood, C. S. & Koskinen, A. M. P., 2014, In : European Journal of Organic Chemistry. 2014, 11, p. 2357-2364

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
13 Citations (Scopus)
89 Downloads (Pure)
2013

Diastereoselective Intramolecular Allyl Transfer from Allyl Carbamate Accompanied by 5-endo-trig Ring Closure

Karjalainen, O. K., Nieger, M. & Koskinen, A. M. P., 2013, In : Angewandte Chemie. 52, 9, p. 2551-2554

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
7 Citations (Scopus)
306 Downloads (Pure)

Efficient, Stereodivergent Access to 3-Piperidinols by Traceless P(OEt)3 Cyclodehydration

Huy, P. & Koskinen, A., 2013, In : ORGANIC LETTERS. 15, p. 51785181

Research output: Contribution to journalArticleScientificpeer-review

23 Citations (Scopus)

Garner’s aldehyde as a versatile intermediate in the synthesis of enantiopure natural products

Passiniemi, M. & Koskinen, A., 2013, In : BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY. 9, p. 2641-2659

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
31 Citations (Scopus)
119 Downloads (Pure)

Stereocontrolled construction of decahydro quinoline ring systems: the case of lepadin alkaloids (Review)

Pelss, A. & Koskinen, A. M. P., 2013, In : CHEMISTRY OF HETEROCYCLIC COMPOUNDS. 49, 2, p. 226-240

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
8 Citations (Scopus)
264 Downloads (Pure)

tert-Butyl 4-formyl-2,2-dimethyloxazolidine-3-carboxylate

Koskinen, A., 2013, Electronic Encyclopedia of Reagents for Organic Synthesis. Rovis, T. (ed.). Chichester, U.K.: JOHN WILEY & SONS, p. ?

Research output: Chapter in Book/Report/Conference proceedingChapterScientific

2012

Asymmetric Synthesis of Natural Products

Koskinen, A., 2012, 2nd Edition ed. JOHN WILEY & SONS. 322 p.

Research output: Book/ReportBookProfessional

33 Citations (Scopus)

Diastereoselective Synthesis of Vicinal Amino Alcohols

Karjalainen, O. & Koskinen, A., 2012, In : ORGANIC AND BIOMOLECULAR CHEMISTRY. 10, p. 43114326

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
77 Citations (Scopus)
176 Downloads (Pure)
2011

Asymmetric synthesis of Pachastrissamine (Jaspine B) and its diastereomers via ?3-allylpalladium intermediates

Passiniemi, M. & Koskinen, A. M. P., 2011, In : ORGANIC AND BIOMOLECULAR CHEMISTRY. 9, 6, p. 1774-1783

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
48 Citations (Scopus)
105 Downloads (Pure)

Chirospecific synthesis: Catalysis and chiral pool hand in hand

Koskinen, A. M. P., 2011, In : Pure and Applied Chemistry. 83, 3, p. 435-443

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
6 Citations (Scopus)
123 Downloads (Pure)

Demethylation of Aromatic Methyl Ethers Using Ionic Liquids under Microwave Irradiation

Passiniemi, M., Myllymaki, M. J., Vuokko, J. & Koskinen, A. M. P., 2011, In : Letters in Organic Chemistry. 8, 1, p. 48-52

Research output: Contribution to journalArticleScientificpeer-review

6 Citations (Scopus)

Enantioselective synthesis of Boc-protected norfuranomycins

Passiniemi, M. & Koskinen, A. M. P., 14 Dec 2011, In : Tetrahedron Letters. 52, 50, p. 6736-6738 3 p.

Research output: Contribution to journalArticleScientificpeer-review

4 Citations (Scopus)

Enantioselective synthesis of norfuranomycins

Passiniemi, M. & Koskinen, A. M. P., 2011, In : Tetrahedron Letters. 52, 50, p. 6736-6738

Research output: Contribution to journalArticleScientificpeer-review

Rapid and practical synthesis of (-)-1-deoxyaltronojirimycin

Karjalainen, O. K. & Koskinen, A. M. P., 2011, In : ORGANIC AND BIOMOLECULAR CHEMISTRY. 9, 4, p. 1231-1236

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
23 Citations (Scopus)
130 Downloads (Pure)
2010

3-Heterocycle-Phenyl N-Alkylcarbamates as FAAH Inhibitors: Design, Synthesis and 3D-QSAR Studies

Kasnanen, H., Myllymaki, M. J., Minkkila, A., Kataja, A. O., Saario, S. M., Nevalainen, T., Koskinen, A. M. P. & Poso, A., 2010, In : CHEMMEDCHEM. 5, 2, p. 213-231

Research output: Contribution to journalArticleScientificpeer-review

12 Citations (Scopus)

A short and efficient synthesis of (2S,3S,4S)-tert-butyl 3,4-dihydroxy-2-(methoxymethyl)-5-oxopyrrolidine-1-carboxylate

Passiniemi, M. & Koskinen, A. M. P., 2010, In : SYNTHESIS: STUTTGART. 16, p. 2816-2822

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
10 Citations (Scopus)
272 Downloads (Pure)

Asymmetric organocatalytic Michael addition of Meldrum's acid to nitroalkenes: probing the mechanism of bifunctional thiourea organocatalysts

Kataja, A. O. & Koskinen, A. M. P., 2010, In : Arkivoc. p. 205-223

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
8 Citations (Scopus)
88 Downloads (Pure)

Calyculins and Related Marine Natural Products as Serine-Threonine Protein Phosphatase PP1 and PP2A Inhibitors and Total Syntheses of Calyculin A, B, and C

Fagerholm, A. E., Habrant, D. & Koskinen, A. M. P., 2010, In : MARINE DRUGS. 8, 1, p. 122-172

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
44 Citations (Scopus)
139 Downloads (Pure)

Conformational ensembles of flexible beta-turn mimetics in DMSO-d(6)

Koivisto, J. J., Kumpulainen, E. T. T. & Koskinen, A. M. P., 2010, In : ORGANIC AND BIOMOLECULAR CHEMISTRY. 8, 9, p. 2103-2116

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
15 Citations (Scopus)
86 Downloads (Pure)

Conversion of carbonyl compounds to alkynes: general overview and recent developments

Habrant, D., Rauhala, V. & Koskinen, A. M. P., 2010, In : CHEMICAL SOCIETY REVIEWS. 39, 6, p. 2007-2017

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
84 Citations (Scopus)
178 Downloads (Pure)

Enantioselective Synthesis of Homosphingosine Derivatives from L-Aspartic Acid

Sauerland, S. J. K., Castillo-Melendez, J. A., Nattinen, K., Rissanen, K. & Koskinen, A. M. P., 2010, In : SYNTHESIS: STUTTGART. 5, p. 757-762

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
8 Citations (Scopus)
126 Downloads (Pure)

Short and Straightforward Synthesis of (-)-1-Deoxygalactonojirimycin

Karjalainen, O. K., Passiniemi, M. & Koskinen, A. M. P., 2010, In : ORGANIC LETTERS. 12, 6, p. 1145-1147

Research output: Contribution to journalArticleScientificpeer-review

25 Citations (Scopus)

The 9-Phenyl-9-fluorenyl Group for Nitrogen Protection in Enantiospecific Synthesis

Karppanen, E. J. & Koskinen, A. M. P., 2010, In : MOLECULES. 15, 9, p. 6512-6547

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
10 Citations (Scopus)
115 Downloads (Pure)

Towards the total synthesis of calyculin C: Preparation of the C9-C25 spiroketal-dipropionate unit

Habrant, D. & Koskinen, A. M. P., 2010, In : ORGANIC AND BIOMOLECULAR CHEMISTRY. 8, 19, p. 4364-4373

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
6 Citations (Scopus)
113 Downloads (Pure)
2009

A Simple Organocatalytic Enantioselective Synthesis of Pregabalin

Bassas, O., Huuskonen, J., Rissanen, K. & Koskinen, A. M. P., 2009, In : European Journal of Organic Chemistry. 9, p. 1340-1351

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
73 Citations (Scopus)
281 Downloads (Pure)

Catalytic Activity Dependency on Catalyst Components in Aerobic Copper-TEMPO Oxidation

Kumpulainen, E. T. T. & Koskinen, A. M. P., 2009, In : CHEMISTRY: A EUROPEAN JOURNAL. 15, 41, p. 10901-10911

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
156 Citations (Scopus)
390 Downloads (Pure)

Chiral 3-(4,5-dihydrooxazol-2-yl)phenyl alkylcarbamates as novel FAAH inhibitors: Insight into FAAH enantioselectivity by molecular docking and interaction fields

Myllymaki, M. J., Kasnanen, H., Kataja, A. O., Lahtela-Kakkonen, M., Saario, S. M., Poso, A. & Koskinen, A. M. P., 2009, In : EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 44, 10, p. 4179-4191

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
17 Citations (Scopus)
317 Downloads (Pure)

Highly Chemoselective Copper-Catalyzed Conjugate Reduction of Stereochemically Labile alpha,beta-Unsaturated Amino Ketones

Pelss, A., Kumpulainen, E. T. T. & Koskinen, A. M. P., 2009, In : Journal of organic chemistry. 74, 19, p. 7598-7601

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
266 Downloads (Pure)

Polyhydroxylated indolizidine alkaloids-synthesis of dideoxycastanospermine

Koskinen, A. M. P., Kallatsa, O. A. & Nissinen, M., 2009, In : Tetrahedron. 65, 45, p. 9285-9290

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
6 Citations (Scopus)
290 Downloads (Pure)

Synthesis and agonist properties of novel quinoline and isoquinoline derivatives toward the cannabinoid receptor CB2

Reux, B., Nevalainen, T., Raitio, K. H. & Koskinen, A. M. P., 2009, In : BIOORGANIC AND MEDICINAL CHEMISTRY. 17, 13, p. 4441-4447

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
320 Downloads (Pure)

The synthesis and biological evaluation of para-substituted phenolic N-alkyl carbamates as endocannabinoid hydrolyzing enzyme inhibitors

Minkkila, A., Myllymaki, M. J., Saario, S. M., Castillo-Melendez, J. A., Koskinen, A. M. P., Fowler, C. J., Leppanen, J. & Nevalainen, T., 2009, In : EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 44, 7, p. 2994-3008

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
23 Citations (Scopus)
312 Downloads (Pure)

Towards the total synthesis of Calyculin C: preparation of the C-13-C-25 spirocyclic core

Habrant, D., Stewart, A. J. W. & Koskinen, A. M. P., 2009, In : Tetrahedron. 65, 38, p. 7927-7934

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
11 Citations (Scopus)
288 Downloads (Pure)
2008

4-substituted phenololic N-Alkyl carabamates as Faah and MGL inhibitors

Minkkilä, A., Myllymäki, M. J., Käsnänen, H., Saario, S. M., Koskinen, A. M. P., Poso, A. & Nevalainen, T., 2008, Vilnius, Lithuania, (5th Biannual Balticum Organicum Syntheticum, Vilnius, Lithuania, June 29 - July 2, 2008).

Research output: Working paperProfessional