Ari Koskinen

Professor

Research outputs

  1. 2019
  2. Published

    Synthesis of the C1-C12 Fragment of Calyculin C

    Konstantinova, O. V. & Koskinen, A. M. P., 1 Jan 2019, In : Synthesis (Germany). 51, 1, p. 285-295 11 p.

    Research output: Contribution to journalArticleScientificpeer-review

  3. 2018
  4. Published

    Copper Catalyzed Alcohol Oxidation and Cleavage of β-O-4 Lignin Model Systems: From Development to Mechanistic Examination

    Salonen, H. E. P., Mecke, C. P. A., Karjomaa, M. I., Joensuu, P. M. & Koskinen, A. M. P., 30 Nov 2018, In : ChemistrySelect. 3, 44, p. 12446-12454 9 p.

    Research output: Contribution to journalArticleScientificpeer-review

  5. 2015
  6. Published

    Discovery of MINC1, a GTPase-Activating Protein Small Molecule Inhibitor, Targeting MgcRacGAP

    van Adrichem, A. J., Fagerholm, A., Turunen, L., Lehto, A., Saarela, J., Koskinen, A., Repasky, G. A. & Wennerberg, K., 2015, In : COMBINATORIAL CHEMISTRY AND HIGH THROUGHPUT SCREENING. 18, 1, p. 3-17

    Research output: Contribution to journalArticleScientificpeer-review

  7. Published

    Enantiospecific Gram Scale Synthesis of (S)-Eleagnine

    Lood, C. S., Nieger, M. & Koskinen, A. M. P., 2015, In : Tetrahedron. 71, 30, p. 5019-5024

    Research output: Contribution to journalArticleScientificpeer-review

  8. Published
  9. Published

    Palladium Catalyzed Direct C-H Arylation of Dicyanobenzenes

    Ihanainen, N. E., Kumpulainen, E. T. T. & Koskinen, A. M. P., 2015, In : European Journal of Organic Chemistry. 2015, 15, p. 3226-3229

    Research output: Contribution to journalArticleScientificpeer-review

  10. Published

    Synthesis of chiral 2-indolyl methanamines and insight into the stereochemistry protecting effects of the 9-phenyl-9-fluorenyl protecting group

    Lood, C. S., Laine, A. E., Högnäsbacka, A., Nieger, M. & Koskinen, A. M. P., 2015, In : European Journal of Organic Chemistry. 2015, 17, p. 3793-3805

    Research output: Contribution to journalArticleScientificpeer-review

  11. Published

    The Tishchenko Reaction

    Koskinen, A. M. P. & Kataja, A. O., 2015, Organic Reactions. 1 ed. John Wiley and Sons Inc., Vol. 86. p. 105-409 305 p. (Organic Reactions; vol. 86, no. 1).

    Research output: Chapter in Book/Report/Conference proceedingChapterScientificpeer-review

  12. Published

    Upgrading fast pyrolysis bio-oil quality by esterification and azeotropic water removal

    Sundqvist, T., Oasmaa, A. & Koskinen, A., 2015, In : Energy and Fuels. 29, 4, p. 2527-2534

    Research output: Contribution to journalArticleScientificpeer-review

  13. Published

    Versatile Synthesis of Symmetrical Carbazole Based Ligand Precursors via Regioselective Aromatic Bromination

    Rembiak, A. & Koskinen, A. M. P., 2015, In : SYNTHESIS: STUTTGART. 47, 21, p. 3347-3353

    Research output: Contribution to journalArticleScientificpeer-review

  14. 2014
  15. Published

    Development of a proof-of-concept small molecule inhibitor of MgcRacGAP identifies new potential functions of MgcRacGAP in cell division and signaling

    van Adrichem, A., Fagerholm, A., Turunen, L., Lehto, A., Saarela, J., Koskinen, A., Repasky, G. & Wennerberg, K., Dec 2014, In : MOLECULAR BIOLOGY OF THE CELL. 25, 1 p.

    Research output: Contribution to journalMeeting AbstractScientificpeer-review

  16. Published

    Erratum: Synthesis of (S)- and (R)-Harmicine from Proline: An Approach Toward Tetrahydro-beta-carbolines

    Lood, C. S. & Koskinen, A. M. P., Aug 2014, 1 p.

    Research output: Other contributionScientificpeer-review

  17. Published

    Boron Enolate Chemistry toward the Syntheses of Polyketide Stereotetrads

    Koskinen, A. M. P., 2014, In : CHEMICAL RECORD. 14, 1, p. 52-61

    Research output: Contribution to journalArticleScientificpeer-review

  18. Published
  19. Published

    Pharmacological Importance of Optically Active Tetrahydro-beta-carbolines and Synthetic Approaches to Create the C1 Stereocenter

    Laine, A. E., Lood, C. & Koskinen, A. M. P., 2014, In : MOLECULES. 19, 2, p. 1544-1567

    Research output: Contribution to journalReview ArticleScientificpeer-review

  20. Published

    Scalable synthesis of (-)-trans-3-hydroxypipecolic acid via a useful chiral building block

    Karjalainen, O. K. & Koskinen, A. M. P., 2014, In : Tetrahedron. 70, 14, p. 2444-2448

    Research output: Contribution to journalArticleScientificpeer-review

  21. Published

    Synthesis of ( S)-and ( R)- Harmicine from Proline: An Approach Toward Tetrahydro- beta- carbolines

    Lood, C. S. & Koskinen, A. M. P., 2014, In : European Journal of Organic Chemistry. 2014, 11, p. 2357-2364

    Research output: Contribution to journalArticleScientificpeer-review

  22. 2013
  23. Published

    Diastereoselective Intramolecular Allyl Transfer from Allyl Carbamate Accompanied by 5-endo-trig Ring Closure

    Karjalainen, O. K., Nieger, M. & Koskinen, A. M. P., 2013, In : Angewandte Chemie. 52, 9, p. 2551-2554

    Research output: Contribution to journalArticleScientificpeer-review

  24. Published

    Efficient, Stereodivergent Access to 3-Piperidinols by Traceless P(OEt)3 Cyclodehydration

    Huy, P. & Koskinen, A., 2013, In : ORGANIC LETTERS. 15, p. 51785181

    Research output: Contribution to journalArticleScientificpeer-review

  25. Published

    Garner’s aldehyde as a versatile intermediate in the synthesis of enantiopure natural products

    Passiniemi, M. & Koskinen, A., 2013, In : BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY. 9, p. 2641-2659

    Research output: Contribution to journalArticleScientificpeer-review

  26. Published

    Stereocontrolled construction of decahydro quinoline ring systems: the case of lepadin alkaloids (Review)

    Pelss, A. & Koskinen, A. M. P., 2013, In : CHEMISTRY OF HETEROCYCLIC COMPOUNDS. 49, 2, p. 226-240

    Research output: Contribution to journalArticleScientificpeer-review

  27. Published

    tert-Butyl 4-formyl-2,2-dimethyloxazolidine-3-carboxylate

    Koskinen, A., 2013, Electronic Encyclopedia of Reagents for Organic Synthesis. Rovis, T. (ed.). Chichester, U.K., p. ?

    Research output: Chapter in Book/Report/Conference proceedingChapterScientific

  28. 2012
  29. Published

    Asymmetric Synthesis of Natural Products

    Koskinen, A., 2012, 2nd Edition ed. 322 p.

    Research output: Book/ReportBookProfessional

  30. Published

    Diastereoselective Synthesis of Vicinal Amino Alcohols

    Karjalainen, O. & Koskinen, A., 2012, In : ORGANIC AND BIOMOLECULAR CHEMISTRY. 10, p. 43114326

    Research output: Contribution to journalArticleScientificpeer-review

  31. 2011
  32. Published

    Enantioselective synthesis of Boc-protected norfuranomycins

    Passiniemi, M. & Koskinen, A. M. P., 14 Dec 2011, In : Tetrahedron Letters. 52, 50, p. 6736-6738 3 p.

    Research output: Contribution to journalArticleScientificpeer-review

  33. Published

    Asymmetric synthesis of Pachastrissamine (Jaspine B) and its diastereomers via ?3-allylpalladium intermediates

    Passiniemi, M. & Koskinen, A. M. P., 2011, In : ORGANIC AND BIOMOLECULAR CHEMISTRY. 9, 6, p. 1774-1783

    Research output: Contribution to journalArticleScientificpeer-review

  34. Published

    Chirospecific synthesis: Catalysis and chiral pool hand in hand

    Koskinen, A. M. P., 2011, In : Pure and Applied Chemistry. 83, 3, p. 435-443

    Research output: Contribution to journalArticleScientificpeer-review

  35. Published

    Demethylation of Aromatic Methyl Ethers Using Ionic Liquids under Microwave Irradiation

    Passiniemi, M., Myllymaki, M. J., Vuokko, J. & Koskinen, A. M. P., 2011, In : Letters in Organic Chemistry. 8, 1, p. 48-52

    Research output: Contribution to journalArticleScientificpeer-review

  36. Published

    Enantioselective synthesis of norfuranomycins

    Passiniemi, M. & Koskinen, A. M. P., 2011, In : Tetrahedron Letters. 52, 50, p. 6736-6738

    Research output: Contribution to journalArticleScientificpeer-review

  37. Published

    Rapid and practical synthesis of (-)-1-deoxyaltronojirimycin

    Karjalainen, O. K. & Koskinen, A. M. P., 2011, In : ORGANIC AND BIOMOLECULAR CHEMISTRY. 9, 4, p. 1231-1236

    Research output: Contribution to journalArticleScientificpeer-review

  38. 2010
  39. Published

    3-Heterocycle-Phenyl N-Alkylcarbamates as FAAH Inhibitors: Design, Synthesis and 3D-QSAR Studies

    Kasnanen, H., Myllymaki, M. J., Minkkila, A., Kataja, A. O., Saario, S. M., Nevalainen, T., Koskinen, A. M. P. & Poso, A., 2010, In : CHEMMEDCHEM. 5, 2, p. 213-231

    Research output: Contribution to journalArticleScientificpeer-review

  40. Published

    A short and efficient synthesis of (2S,3S,4S)-tert-butyl 3,4-dihydroxy-2-(methoxymethyl)-5-oxopyrrolidine-1-carboxylate

    Passiniemi, M. & Koskinen, A. M. P., 2010, In : SYNTHESIS: STUTTGART. 16, p. 2816-2822

    Research output: Contribution to journalArticleScientificpeer-review

  41. Published

    Asymmetric organocatalytic Michael addition of Meldrum's acid to nitroalkenes: probing the mechanism of bifunctional thiourea organocatalysts

    Kataja, A. O. & Koskinen, A. M. P., 2010, In : Arkivoc. p. 205-223

    Research output: Contribution to journalArticleScientificpeer-review

  42. Published

    Calyculins and Related Marine Natural Products as Serine-Threonine Protein Phosphatase PP1 and PP2A Inhibitors and Total Syntheses of Calyculin A, B, and C

    Fagerholm, A. E., Habrant, D. & Koskinen, A. M. P., 2010, In : MARINE DRUGS. 8, 1, p. 122-172

    Research output: Contribution to journalArticleScientificpeer-review

  43. Published

    Conformational ensembles of flexible beta-turn mimetics in DMSO-d(6)

    Koivisto, J. J., Kumpulainen, E. T. T. & Koskinen, A. M. P., 2010, In : ORGANIC AND BIOMOLECULAR CHEMISTRY. 8, 9, p. 2103-2116

    Research output: Contribution to journalArticleScientificpeer-review

  44. Published

    Conversion of carbonyl compounds to alkynes: general overview and recent developments

    Habrant, D., Rauhala, V. & Koskinen, A. M. P., 2010, In : CHEMICAL SOCIETY REVIEWS. 39, 6, p. 2007-2017

    Research output: Contribution to journalArticleScientificpeer-review

  45. Published

    Enantioselective Synthesis of Homosphingosine Derivatives from L-Aspartic Acid

    Sauerland, S. J. K., Castillo-Melendez, J. A., Nattinen, K., Rissanen, K. & Koskinen, A. M. P., 2010, In : SYNTHESIS: STUTTGART. 5, p. 757-762

    Research output: Contribution to journalArticleScientificpeer-review

  46. Published

    Short and Straightforward Synthesis of (-)-1-Deoxygalactonojirimycin

    Karjalainen, O. K., Passiniemi, M. & Koskinen, A. M. P., 2010, In : ORGANIC LETTERS. 12, 6, p. 1145-1147

    Research output: Contribution to journalArticleScientificpeer-review

  47. Published

    The 9-Phenyl-9-fluorenyl Group for Nitrogen Protection in Enantiospecific Synthesis

    Karppanen, E. J. & Koskinen, A. M. P., 2010, In : MOLECULES. 15, 9, p. 6512-6547

    Research output: Contribution to journalArticleScientificpeer-review

  48. Published

    Towards the total synthesis of calyculin C: Preparation of the C9-C25 spiroketal-dipropionate unit

    Habrant, D. & Koskinen, A. M. P., 2010, In : ORGANIC AND BIOMOLECULAR CHEMISTRY. 8, 19, p. 4364-4373

    Research output: Contribution to journalArticleScientificpeer-review

  49. 2009
  50. Published

    A Simple Organocatalytic Enantioselective Synthesis of Pregabalin

    Bassas, O., Huuskonen, J., Rissanen, K. & Koskinen, A. M. P., 2009, In : European Journal of Organic Chemistry. 9, p. 1340-1351

    Research output: Contribution to journalArticleScientificpeer-review

  51. Published

    Catalytic Activity Dependency on Catalyst Components in Aerobic Copper-TEMPO Oxidation

    Kumpulainen, E. T. T. & Koskinen, A. M. P., 2009, In : CHEMISTRY: A EUROPEAN JOURNAL. 15, 41, p. 10901-10911

    Research output: Contribution to journalArticleScientificpeer-review

  52. Published

    Chiral 3-(4,5-dihydrooxazol-2-yl)phenyl alkylcarbamates as novel FAAH inhibitors: Insight into FAAH enantioselectivity by molecular docking and interaction fields

    Myllymaki, M. J., Kasnanen, H., Kataja, A. O., Lahtela-Kakkonen, M., Saario, S. M., Poso, A. & Koskinen, A. M. P., 2009, In : EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 44, 10, p. 4179-4191

    Research output: Contribution to journalArticleScientificpeer-review

  53. Published

    Highly Chemoselective Copper-Catalyzed Conjugate Reduction of Stereochemically Labile alpha,beta-Unsaturated Amino Ketones

    Pelss, A., Kumpulainen, E. T. T. & Koskinen, A. M. P., 2009, In : Journal of organic chemistry. 74, 19, p. 7598-7601

    Research output: Contribution to journalArticleScientificpeer-review

  54. Published

    Polyhydroxylated indolizidine alkaloids-synthesis of dideoxycastanospermine

    Koskinen, A. M. P., Kallatsa, O. A. & Nissinen, M., 2009, In : Tetrahedron. 65, 45, p. 9285-9290

    Research output: Contribution to journalArticleScientificpeer-review

  55. Published

    Synthesis and agonist properties of novel quinoline and isoquinoline derivatives toward the cannabinoid receptor CB2

    Reux, B., Nevalainen, T., Raitio, K. H. & Koskinen, A. M. P., 2009, In : BIOORGANIC AND MEDICINAL CHEMISTRY. 17, 13, p. 4441-4447

    Research output: Contribution to journalArticleScientificpeer-review

  56. Published

    The synthesis and biological evaluation of para-substituted phenolic N-alkyl carbamates as endocannabinoid hydrolyzing enzyme inhibitors

    Minkkila, A., Myllymaki, M. J., Saario, S. M., Castillo-Melendez, J. A., Koskinen, A. M. P., Fowler, C. J., Leppanen, J. & Nevalainen, T., 2009, In : EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 44, 7, p. 2994-3008

    Research output: Contribution to journalArticleScientificpeer-review

  57. Published

    Towards the total synthesis of Calyculin C: preparation of the C-13-C-25 spirocyclic core

    Habrant, D., Stewart, A. J. W. & Koskinen, A. M. P., 2009, In : Tetrahedron. 65, 38, p. 7927-7934

    Research output: Contribution to journalArticleScientificpeer-review

  58. 2008
  59. Published

    4-substituted phenololic N-Alkyl carabamates as Faah and MGL inhibitors

    Minkkilä, A., Myllymäki, M. J., Käsnänen, H., Saario, S. M., Koskinen, A. M. P., Poso, A. & Nevalainen, T., 2008, Vilnius, Lithuania, (5th Biannual Balticum Organicum Syntheticum, Vilnius, Lithuania, June 29 - July 2, 2008).

    Research output: Working paperProfessional

  60. Published

    A new application for PyOX-ligands: The asymmetric Henry reaction

    Oila, M. J., Tois, J. E. & Koskinen, A. M. P., 2008, In : Letters in Organic Chemistry. 5, 1, p. 11-16

    Research output: Contribution to journalArticleScientificpeer-review

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