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Personal profile

Artistic and research interests

Professor Ari M.P.Koskinen was born on September 22, 1956 in Finland. He received his M.Sc. (Chem. Eng.) in 1979 (with professor T. Hase, development of the synthesis of alkyl tert-alkyl ethers for anti-knock agents), Licentiate in Technology in 1982 and Doctor of Technology in 1983 (with professor M. Lounasmaa, methodology development on the modified Polonovski reaction for indole alkaloid synthesis), all at the Helsinki University of Technology, Finland. After postdoctoral studies at the University of California, Berkeley (professor Henry Rapoport 1983-85 and 1987-88, total synthesis of anatoxin-a, and conformationally constrained peptidomimetics) he accepted an appointment as a Project Leader in New Drug Development at Orion Corporation – Fermion, Finland (1985-1987). His research group was among the first in Scandinavia to adopt computer aided drug design (QSAR and CoMFA) as well as computerized database handling protocols in new lead identification. Returning to the Academia, he joined the University of Surrey, England, as a lecturer in 1989. He was then appointed as Professor of Chemistry (especially Synthetic Organic Chemistry) at the University of Oulu, Finland in 1992, and transferred to his current position at the Helsinki University of Technology in August, 1999 as Professor of Organic Chemistry (the old Gustav Komppa chair). Prof. Koskinen is a member of the Finnish Academy of Sciences and Letters since 2003. He is the author or co-author of some 190 publications, ten patents and two books.

His research ointerests include the development of novel synthetic methods especially in the field of enantioselective synthesis. A long standing project has centered on the transfer chirality information to new stereocenters on the synthesized molecule utilizing only the existing chiral information in the starting material (internal asymetric induction). The starting materials are selected from readily available, renewable natural compounds (amino acids), and the target compounds are natural  products or their analoges with biological significance. Over the years, a number of alkaloids, sphingosine like compounds and imino sugars have been synthesized.

Supervision of post-doc researchers

I have supervised a total of 38 post doctoral researchers during my career as a professor (first at the University of Oulu, and since 2000 at TKK/Aalto). They are:

Bauer, Martin
Bauer, Udo
Chen, Jingshan
Cura, Peter
Edmonds, Michael
Gefflaut, Thierry
Ghiaci, Mehran
Harden, Grahame
Hatam, Mostafa
Kamel, M.S.
Karvinen, Esko
Krische, M.J.
Lajunen, Marja
Munoz, Luis
Nevalainen, Marta
Page, Patrick
Psiorz, Christian
Schwerdtfeger, Jörg
Xia, Zhi-Qiang
Castillo, Joel
Straub, Thomas
Helaja, Juho
Koivisto, Jari
Rajamäki, Suvi
Tois, Jan
Monfray, Jeremy
Stewart, Alan
Bassas, Oriol
Reux, Bastien
Habrant, Damien
Linden, Auri
Chiesa, Katja
Huy, Peter
Venkatesh, K.B.
Tsoukala, Anna
Venkatesh, K.B.
Rembiak, Andreas
Konstantinova, Olga

Expertise related to UN Sustainable Devlopment Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 7 - Affordable and Clean Energy
  • SDG 14 - Life Below Water

Education/Academic qualification

Doctoral degree, Engineering and Technology, Helsinki University of Technology

Award Date: 2 Jun 1983

Licentiate degree, Engineering and Technology, Helsinki University of Technology

Award Date: 20 Apr 1982

Master's degree, Engineering and Technology, Helsinki University of Technology

Award Date: 6 Feb 1979

Keywords

  • Organic chemistry
  • Natural products
  • Asymmetric synthesis

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