Research Output per year
Research Output per year
Organization profile
Profile Information
The overall objective of the CoE is to understand the molecular mechanisms that control the immune system as well as the interactions between the immune system and other physiological systems in health and disease. This information may help in prevention and treatment of inflammatory and immune-mediated disorders. The CoE will focus especially on type 1 diabetes. Along the way, the research will generate new knowledge of the role of metabolism in early stages of autoimmune diseases as well as reveal novel molecular mechanisms.
The Centre of Excellence (CoE) is directed by Professor Mikael Knip from the University of Helsinki. Professor Harri Lähdesmäki from the Aalto University School of Science is leading the research group in the CoE.
Read more (http://symmys.fi)
Fingerprint
Dive into the research topics where Centre of Excellence in Molecular Systems Immunology and Physiology Research Group, SyMMys is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Profiles
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Lu Cheng
- Centre of Excellence in Computational Inference, COIN - Postdoctoral Researcher
- Professorship Lähdesmäki H. - Academy Research Fellow
- Centre of Excellence in Molecular Systems Immunology and Physiology Research Group, SyMMys
- Department of Computer Science - Academy Research Fellow
Person: Postdoctoral researchers
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Viivi Halla-aho
- Professorship Lähdesmäki H. - Doctoral Candidate
- Centre of Excellence in Molecular Systems Immunology and Physiology Research Group, SyMMys
- School services, SCI
- Department of Computer Science - Doctoral Candidate
Person: Doctoral students, Doctoral studies
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Markus Heinonen
- Professorship Lähdesmäki H. - Research Fellow
- Centre of Excellence in Molecular Systems Immunology and Physiology Research Group, SyMMys
- Department of Computer Science - Research Fellow
Person: Postdoctoral researchers
Research Output
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Adult-Onset Anti-Citrullinated Peptide Antibody-Negative Destructive Rheumatoid Arthritis Is Characterized by a Disease-Specific CD8+ T Lymphocyte Signature
Kelkka, T., Savola, P., Bhattacharya, D., Huuhtanen, J., Lönnberg, T., Kankainen, M., Paalanen, K., Tyster, M., Lepistö, M., Ellonen, P., Smolander, J., Eldfors, S., Yadav, B., Khan, S., Koivuniemi, R., Sjöwall, C., Elo, L. L., Lähdesmäki, H., Maeda, Y., Nishikawa, H. & 3 others, , 19 Nov 2020, In : FRONTIERS IN IMMUNOLOGY. 11, 12 p., 578848.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
A personalised approach for identifying disease-relevant pathways in heterogeneous diseases
Somani, J., Ramchandran, S. & Lähdesmäki, H., 1 Dec 2020, In : npj Systems Biology and Applications. 6, 1, 17.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Deep Convolutional Gaussian Processes
Blomqvist, K., Kaski, S. & Heinonen, M., 1 Jan 2020, Machine Learning and Knowledge Discovery in Databases - European Conference, ECML PKDD 2019, Proceedings. Brefeld, U., Fromont, E., Hotho, A., Knobbe, A., Maathuis, M. & Robardet, C. (eds.). p. 582-597 16 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 11907 LNAI).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific › peer-review
Open Access
Datasets
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The influence of a short-term gluten-free diet on the human gut microbiome
Bonder, M. J. (Creator), Tigchelaar, E. F. (Contributor), Cai, X. (Contributor), Trynka, G. (Contributor), Cenit, M. C. (Contributor), Hrdlickova, B. (Contributor), Zhong, H. (Contributor), Vatanen, T. (Contributor), Gevers, D. (Contributor), Wijmenga, C. (Contributor), Wang, Y. (Contributor) & Zhernakova, A. (Contributor), 1 Jan 2016
DOI: 10.6084/m9.figshare.c.3598283.v1, https://figshare.com/collections/The_influence_of_a_short-term_gluten-free_diet_on_the_human_gut_microbiome/3598283/1
Dataset
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A probabilistic generative model for quantification of DNA modifications enables analysis of demethylation pathways
Äijö, T. (Contributor), Huang, Y. (Contributor), Mannerström, H. (Contributor), Chavez, L. (Contributor), Tsagaratou, A. (Contributor), Rao, A. (Contributor) & Lähdesmäki, H. (Contributor), 1 Jan 2016
DOI: 10.6084/m9.figshare.c.3604346.v1, https://figshare.com/collections/A_probabilistic_generative_model_for_quantification_of_DNA_modifications_enables_analysis_of_demethylation_pathways/3604346/1
Dataset
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Genome wide analysis of protein production load in Trichoderma reesei
Pakula, T. M. (Contributor), Nygren, H. (Contributor), Barth, D. (Contributor), Heinonen, M. (Contributor), Castillo, S. (Contributor), Penttilä, M. (Creator) & Arvas, M. (Contributor), 1 Jan 2016
DOI: 10.6084/m9.figshare.c.3603251.v1, https://figshare.com/collections/Genome_wide_analysis_of_protein_production_load_in_Trichoderma_reesei/3603251/1
Dataset
Activities
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International Conference on Machine Learning
Maria Osmala (Member)
12 Jul 2020 → 18 Jul 2020Activity: Participating in or organising an event types › Participant of a conference, workshop, session or tutorial
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Faster Bayesian inference in Joint Species Distribution Models
Gleb Tikhonov (Speaker), Jarno Vanhatalo (Contributor), Otso Ovaskainen (Contributor) & Harri Lähdesmäki (Contributor)
22 Jun 2020 → 26 Jun 2020Activity: Talk or presentation types › Conference presentation
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Enhancer prediction in the human genome using supervised probabilistic modelling of epigenetic data
Maria Osmala (Speaker)
22 Jul 2019 → 23 Jul 2019Activity: Talk or presentation types › Conference presentation
Press / Media
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Could bacteria-attacking viruses hold a clue to obesity?
15/03/2020
3 items of Media coverage
Press/Media: Media appearance
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University of Auckland welcomes Te Pūtea Rangahau a Marsden 5 November 2019
05/11/2019
1 item of Media coverage
Press/Media: Media appearance
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New findings about the gut microbiome in infants and children
04/06/2019
1 item of Media coverage
Press/Media: Media appearance