Data from: Cryptic ecology among host generalist Campylobacter jejuni in domestic animals

  • Samuel K. Sheppard (Contributor)
  • Lu Cheng (Contributor)
  • Guillaume Méric (Contributor)
  • Caroline Haan (Contributor)
  • Ann-Katrin Llarena (Contributor)
  • Pekka Marttinen (Contributor)
  • Ana Vidal (Contributor)
  • Anne Ridley (Contributor)
  • Felicity Clifton-Hadley (Contributor)
  • Thomas R. Connor (Contributor)
  • Norval Strachan (Creator)
  • Ken Forbes (Creator)
  • Frances Colles (Creator)
  • Keith Jolley (Creator)
  • Stephen Bentley (Creator)
  • Martin Maiden (Creator)
  • Marja-Liisa Hänninen (Creator)
  • Julian Parkhill (Creator)
  • William Hanage (Creator)
  • Jukka Corander (Creator)

    Dataset

    Description

    Homologous recombination between bacterial strains is theoretically capable of preventing the separation of daughter clusters, and producing cohesive clouds of genotypes in sequence space. However, numerous barriers to recombination are known. Barriers may be essential such as adaptive incompatibility, or ecological, which is associated with the opportunities for recombination in the natural habitat. Campylobacter jejuni is a gut colonizer of numerous animal species and a major human enteric pathogen. We demonstrate that the two major generalist lineages of C. jejuni do not show evidence of recombination with each other in nature, despite having a high degree of host niche overlap and recombining extensively with specialist lineages. However, transformation experiments show that the generalist lineages readily recombine with one another in vitro. This suggests ecological rather than essential barriers to recombination, caused by a cryptic niche structure within the hosts.
    Date made available28 Mar 2014
    PublisherDryad Digital Repository

    Research Output

    Cryptic ecology among host generalist Campylobacter jejuni in domestic animals

    Sheppard, S. K., Cheng, L., Méric, G., Haan, C., Llarena, A-K., Marttinen, P., Vidal, A., Ridley, A., Clifton-Hadley, F. & Connor, T. R., 2014, In : MOLECULAR ECOLOGY. 23, 10, p. 2442-2451

    Research output: Contribution to journalArticleScientificpeer-review

    55 Citations (Scopus)

    Cite this

    Sheppard, S. K. (Contributor), Cheng, L. (Contributor), Méric, G. (Contributor), Haan, C. (Contributor), Llarena, A. (Contributor), Marttinen, P. (Contributor), Vidal, A. (Contributor), Ridley, A. (Contributor), Clifton-Hadley, F. (Contributor), Connor, T. R. (Contributor), Strachan, N. (Creator), Forbes, K. (Creator), Colles, F. (Creator), Jolley, K. (Creator), Bentley, S. (Creator), Maiden, M. (Creator), Hänninen, M. (Creator), Parkhill, J. (Creator), Hanage, W. (Creator), Corander, J. (Creator) (28 Mar 2014). Data from: Cryptic ecology among host generalist Campylobacter jejuni in domestic animals. Dryad Digital Repository. 10.5061/dryad.hk860